A combined analysis of the Deleted in Colon Cancer (DCC) and the p53 proteins expression in gastric cancer

نویسندگان

  • Francesco Graziano
  • Maria Pia Staccioli
  • Anna Maria Baldelli
  • Stefano Cascinu
  • Vincenzo Catalano
  • Maria Cristina Rossi
  • Paolo Giordani
  • Pietro Muretto
  • Giuseppina Catalano
چکیده

Title: A combined analysis of the Deleted in Colon Cancer (DCC) and the p53 proteins expression in gastric cancer. Summary Background: Loss of acitivity of tumor suppressor genes is considered a fundamental step in a genetic model of

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Investigation of Network of Proteins Effective in Esophageal, Gastric and Colon Cancers and Determination of Key Common Proteins Using In Silico Method

Introduction: The prevalence of gastrointestinal cancers, especially gastric and colorectal cancers, is increasing. Gastric cancer is the most common gastrointestinal cancer in Iran and the age of esophageal and colon cancers onset has decreased in Iran. Therefore, it is important to study the factors and proteins involved in these cancers. Use of computational tools is an effective way to stud...

متن کامل

Investigation of Network of Proteins Effective in Esophageal, Gastric and Colon Cancers and Determination of Key Common Proteins Using In Silico Method

Introduction: The prevalence of gastrointestinal cancers, especially gastric and colorectal cancers, is increasing. Gastric cancer is the most common gastrointestinal cancer in Iran and the age of esophageal and colon cancers onset has decreased in Iran. Therefore, it is important to study the factors and proteins involved in these cancers. Use of computational tools is an effective way to stud...

متن کامل

Changes in monocarboxylate transporter 1 and p53 gene expression by aerobic interval training in the experimental colon carcinoma of mouse

Background: Recent evidence suggests that regular exercise training is effective in treating various aspects of cancer. Therefore, the purpose of this study was to determine the effect of 8 weeks of aerobic interval training on monocarboxylate transporter 1 (MCT1) protein and expression of p53 gene in tumor of colon cancer mice. Methods: The present study was conducted experimentally from May ...

متن کامل

Effects of Trichostatin A on the Histone Deacetylases (HDACs), Intrinsic Apoptotic Pathway, p21/Waf1/Cip1, and p53 in Human Neuroblastoma, Glioblastoma, Hepatocellular Carcinoma, and Colon Cancer Cell Lines

Background:  The aberrant and altered patterns of gene expression play an important role in the biology of cancer and tumorigenesis. DNA methylation and histone deacetylation are the most studied epigenetic mechanisms. Histone deacetylase inhibitors (HDACIs) such as valproic acid (VPA) and trichostatin A (TSA) are a group of anticancer compounds for the treatment of solid and hematological canc...

متن کامل

شناسایی پروتئین‌های کلیدی درگیر در بروز سرطان معده به روش In silico

Background: Gastric cancer is the first most common cancer death in Iran. There have been many efforts in finding the most effective proteins in this cancer. Using the proteins identified in gastric cancer combined with advanced computational tools in analyzing biological networks, we have developed a rational method in order to identify candidate proteins associated with this cancer. Materi...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2001